PDRN polynucleotide skin renewal — the physician-administered bio-stimulating treatment that repairs DNA, restores your skin barrier and reverses the earliest signs of ageing from within.
Rejuran® is a bio-stimulating treatment based on PDRN (Polydeoxyribonucleotide) — a polynucleotide extracted from salmon DNA that is bio-compatible with human tissue. PDRN activates A2A adenosine receptors in the skin, triggering a cascade of cellular repair, collagen production and anti-inflammatory responses that mirror the body's own healing process.
The Rejuran Facial at Dr Sin Yong's Orchard Road practice is a physician-level protocol — not a beautician facial. The PDRN is delivered through a customised BAP (Bio-Aesthetic Points) injection technique combined with topical serum application and optional micro-needling delivery, targeting the entire face with precision. The result is progressively firmer, more hydrated and visibly younger-looking skin over a series of sessions.
Dr Sin Yong assesses your skin condition, identifies areas of concern and designs your personalised Rejuran protocol — selecting the appropriate delivery method and PDRN concentration for your skin type and goals.
A numbing cream is applied for 20–30 minutes to ensure maximum comfort during the treatment. The Rejuran injection technique, while performed with ultra-fine needles, is well-tolerated by most patients.
Rejuran® is administered using a customised injection technique across the treatment area. Multiple micro-injections deliver PDRN into the superficial dermis, where it is immediately absorbed by fibroblasts and begins stimulating collagen synthesis and DNA repair processes.
A calming, anti-inflammatory serum and hydrating mask are applied post-treatment to support initial healing and maximise the PDRN uptake window. Redness typically resolves within 4–6 hours.
PDRN stimulates A2A receptors triggering cellular regeneration at the DNA level — addressing the root cause of skin ageing rather than masking symptoms.
Clinically proven to significantly increase collagen and elastin production in the dermis, restoring structural support and skin firmness over a 4–8 week period post-treatment.
PDRN strengthens the skin's natural moisture barrier, reducing trans-epidermal water loss and improving the skin's resilience to environmental stressors.
PDRN has potent anti-inflammatory properties, making Rejuran particularly effective for post-acne redness, sensitised skin and rosacea-prone complexions.
Unlike skinboosters that add temporary volume, Rejuran creates structural change — results improve progressively over 6–8 weeks and continue building with each session.
Rejuran's bio-compatible PDRN is safe for all Fitzpatrick skin types. Its anti-inflammatory mechanism actually benefits darker skin tones that are prone to PIH.
Rejuran® is a PDRN (Polydeoxyribonucleotide) bio-stimulating skin treatment available at Dr Sin Yong's Orchard Road practice. It repairs skin DNA, stimulates collagen and restores the skin barrier — addressing fine lines, laxity, dehydration and overall skin health.
An initial course of 3 sessions spaced 4 weeks apart is recommended. Results are progressive — skin improves significantly over 8–12 weeks as collagen synthesis builds. Maintenance sessions every 3–6 months sustain results.
Skinboosters (like Profhilo or Restylane Skinbooster) primarily add hyaluronic acid to improve hydration. Rejuran's PDRN mechanism is fundamentally different — it stimulates the skin's own cellular repair and collagen production. The two treatments can be combined for comprehensive skin health.
Topical anaesthetic cream is applied before the procedure, making it very comfortable for most patients. Some patients experience mild injection sensations, which resolve immediately. There may be minor redness and small papule marks post-treatment that resolve within 4–6 hours.
A conventional facial addresses the skin surface. Rejuran delivers PDRN into the dermis, triggering DNA repair and collagen synthesis at a cellular level — producing structural skin improvement that conventional facials cannot achieve.
Available on Orchard Road, Singapore. By appointment with Dr Sin Yong.
Rejuran healer in Singapore is valued for improving skin texture, elasticity and resilience using polynucleotide technology derived from salmon DNA.