Am I suitable for Rejuran? Scars and texture versus hydration, and Healer, S or I

Who is suitable for Rejuran, and what the assessment looks for

Rejuran delivers polynucleotide, chains of nucleotides purified from salmon DNA, into the dermis by micro-injection. It is directed at the skin's repair environment rather than at its bulk: fibroblast activity, matrix turnover and the signalling that calms inflammation. Nothing in the syringe occupies space or holds a contour. So the suitability question is whether your complaint is about how the skin behaves, which a repair signal can address, or about how much tissue there is, which it cannot. The Rejuran page explains the range; this page answers whether you qualify.

It suits skin that is thin, dull or uneven in texture, with fine lines, loss of elasticity or the surface left behind by acne, in a person who accepts gradual change. Dr Sin Yong examines the skin under good light and under stretch, because post-acne skin has to be sorted before a product is chosen: rolling scars tethered to the dermis, boxcar scars with a fixed wall, ice-pick tracts, and residual redness or pigment that is not scarring at all are treated differently, and a polynucleotide addresses only the skin-quality component. He also asks what has been injected before, and scans with ultrasound where the history includes filler.

Scars and texture versus hydration: is Rejuran the right class?

Rejuran is often requested as a hydrating booster, and that is not quite what it is. Hyaluronic acid boosters bind water in the dermis and answer dull, dehydrated skin directly. Polynucleotides answer a different question: skin whose repair has stalled, whose texture is uneven, whose elasticity has dropped or whose surface still carries the marks of acne. Both are classed as skin boosters and neither is a filler, but a person whose only complaint is dryness is usually better matched to hyaluronic acid, and a person whose complaint is texture and repair is the one for whom polynucleotide earns its place. The skin booster page sets the classes side by side.

For acne scars the order matters more than the product. A scar still tethered to the dermis is released by subcision before any booster goes near it, and the depth of what remains decides whether FSX or the S3 Resurfacing Lift follows. Rejuran S is one component of that plan, not a substitute for it; the Rejuran S page explains where it fits.

“Rejuran signals the skin to repair. It does not fill, it does not lift, and it does not remove pigment. If what you need is one of those three, I will not sell you a repair signal.”

Dr Sin YongOn who is suitable for Rejuran

Fish allergy, keloid tendency and who should wait

The polynucleotide in Rejuran is purified and sterilised from salmon DNA, so what is injected is the polymer, not genetic material, and allergic reaction is rare. It is still the reason fish allergy is asked about directly rather than assumed absent. A documented allergy to fish, or a history of severe allergic reactions of any kind, is discussed before anything is offered, and where the risk is unclear the honest answer is to choose a different class of booster rather than to test it on your face.

Other reasons are about timing. Rejuran is not used in pregnancy or while breastfeeding, and it is not injected through active infection, a cold sore, an acne flare or inflamed skin, which are treated first. A recent laser, peel, filler or thread in the same area is a reason to wait, so that one treatment can be judged before another is added. Where injection is planned into or around scar tissue, a personal or family history of keloid or hypertrophic scarring is weighed before proceeding, because each micro-injection is a small wound; the keloid page explains what that tendency looks like. A bleeding tendency or blood-thinning medicines make bruising more likely, particularly around the eyes, and are reviewed.

Reasons the answer is no rather than later

• Known allergy to fish, to the polynucleotide or to any component of the product
• A goal the product cannot meet: volume, a lift, pigment clearance or smaller pores
• Dark circles that examination shows to be hollowing, shadow or herniated fat rather than skin
• An unmapped earlier filler in the planned area, until it has been scanned

Healer, S or I: which preparation fits which skin

Once the class is right, the preparation follows the tissue. Rejuran Healer is the standard facial preparation, polynucleotide at approximately 20 mg/mL, injected intradermally across the face for texture, fine lines and elasticity. Rejuran S is formulated at a higher viscosity and is intended for scarred skin, where the material is placed into and around the scar rather than spread across a field. Rejuran I is lower in viscosity, intended for the thin skin around the eyes, and Rejuran HB combines polynucleotide with hyaluronic acid so that a repair signal and a hydrating component arrive in one syringe.

Under-eye complaints deserve a separate warning. Hollowing, shadow and herniated fat all present as dark circles and none of them is a skin complaint. Rejuran I addresses crepey lid skin only, and if the examination finds a groove, a fat bag or fluid, the answer lies under tear trough refinement or eye bags, not in a booster.

What decides the plan, if you are suitable

Fees are not advertised, and a figure before examination would describe someone else's skin. What shapes the plan is the area, which preparation the examination points to, whether Rejuran is combined with resurfacing, RF microneedling or subcision, and how the initial and maintenance phases are staged. The how we quote page explains what the written plan contains.

If you are suitable, topical anaesthetic is usual, delivery is by fine needle or an injector device, and small raised points, redness and occasional bruising follow and settle on their own; polynucleotides tend to leave more noticeable bumps at first than a hyaluronic acid booster. Rejuran is often paired with a resurfacing or RF microneedling session in the same plan, as set out under skin boosters with RF microneedling. If you are not suitable, the plan says which class, if any, fits the finding, with the option of no treatment included.