Medically reviewed by Dr Sin Yong · Last reviewed · 8 min read
Published 9 October 2026 · Reviewed by Dr Sin Yong

Ultherapy and Thermage are the two most widely discussed non-surgical tightening treatments, and they work in different ways. Ultherapy focuses ultrasound energy into small points at set depths, down to the muscle-and-fascia layer, while watching on an ultrasound image. Thermage heats the deeper dermis in bulk with monopolar radiofrequency. Two randomised trials have compared them directly.
| Ultherapy | Thermage FLX | |
|---|---|---|
| Energy | Microfocused ultrasound with real-time imaging | Monopolar radiofrequency, 6.78 MHz |
| How heat is placed | Points at set depths: about 4.5, 3.0 and 1.5 mm | Broad heating of the deeper dermis and septa |
| Imaging | Yes, ultrasound visualisation to 8 mm | No |
| Cooling | None needed for focused points | Cryogen spray |
| FDA wording | Lift the eyebrow; lift lax submental and neck tissue; décolleté lines; skin laxity on abdomen, arms and knees | Non-invasive treatment of wrinkles and rhytids, including periorbital |
| Head-to-head evidence | Comparable to monopolar RF in two small randomised trials | Comparable to MFU-V in two small randomised trials |
Ultherapy focuses ultrasound energy into tiny points beneath the skin, the way a magnifying glass focuses light, at depths chosen by the transducer: about 4.5 mm for the muscle-and-fascia layer, 3.0 mm for the deep dermis and 1.5 mm for the superficial dermis. An image on screen helps the operator see the layers. Thermage passes radiofrequency current through the skin to a return pad, heating the deeper dermis and its fibrous septa broadly while cryogen cools the surface. Focused points against a broad field is the core distinction.

In a randomised split-face trial of 20 patients followed for six months, monopolar radiofrequency and microfocused ultrasound both improved laxity with no significant difference between them (Alhaddad, Dermatol Surg 2019). In a trial of 20 patients treated on the neck, results were again not significantly different, and ultrasound was more painful (Jones, Dermatol Surg 2017). Across 42 studies of microfocused ultrasound, 89% reported investigator-assessed improvement, with mean pain of 4.85 out of 10 (Amiri, Aesthet Surg J 2025); in an earlier lower-face study, outcomes were weaker in patients with a body-mass index above 30 (Oni, Aesthet Surg J 2014).

Thermage vs Ultherapy comes down to which layer has loosened. Ultherapy places focused ultrasound at set depths down to the SMAS, with imaging, so it suits laxity that sits deeper along the jaw, under the chin and at the brow. Thermage FLX heats the deeper dermis broadly with monopolar radiofrequency, so it suits crepey skin and early softening of the skin envelope, including the eyelids with its eye tip. Dr Sin Yong performs both Ultherapy Prime and Thermage FLX himself, and the assessment decides which one, both, or neither fits.
| Your situation | Usually leans to | Why |
|---|---|---|
| Early jowling, a softening jawline, laxity under the chin or on the neck | Ultherapy | Reaches the SMAS and platysma at 4.5 mm, with the layers seen on screen first |
| Heaviness at the outer brow | Ultherapy | Brow lift is one of its US-cleared uses; superficial depths above the brow |
| Crepey, thinning skin and fine lines across the cheeks | Thermage FLX | Broad dermal heating suits skin quality more than deep laxity |
| Crepey eyelid skin with a reasonable brow position | Thermage FLX eye tip | A dedicated small tip with shields; heat does not raise a low brow |
| Laxity at two depths: deep jawline plus crepey skin above it | Sometimes both, as separate steps | They act on different layers; order and spacing are set at assessment |
| Lean or hollow face | Usually neither | Heat into fat that is not the target can hollow the face; the VF Lift on Volnewmer is considered instead |
| Puffy or heavier lower face | Usually neither as the main step | Fullness is a fat question; Time Freeze Laser LCLR® is generally used |
| Heavy jowls with redundant skin | Neither | Beyond energy devices; referred for a surgical opinion |
Two small randomised trials found no significant difference between the two for laxity overall, which is why the decision is made on anatomy rather than on reputation. Comfort differs: focused ultrasound is felt as brief, deep heat that is most noticeable over bone, and radiofrequency as heat pulses with cooling bursts. Recovery for both is usually redness and tenderness that settle, with swelling more likely after eye treatment. The Thermage suitability and HIFU suitability guides set out who should wait for each.
Both treatments are usually done without an anaesthetic injection. Ultherapy pulses are felt as deep, brief heat and are more noticeable over bone. Thermage pulses are felt as heat followed by a cooling burst. Redness after either usually settles quickly. After Ultherapy, tenderness on chewing or touch, mild swelling and occasionally small bruises or temporary numbness are recognised, and they are reviewed if they persist.
Uncommon risks for both include:
These are the reasons the energy, the depth and the number of lines are set by the doctor for each zone rather than by a standard package. The fuller lists are on the Ultherapy side effects and Thermage side effects pages. A blister, a new dent over the cheek, temple or jaw, numbness that does not settle, or any change in facial movement should be reported the same day, wherever the treatment was done; the complication care page explains which signs need a doctor the same day.
Volnewmer by CLASSYS is also monopolar radiofrequency at 6.78 MHz, with continuous water cooling rather than cryogen spray. It is the platform behind the VF Lift – Vertical Facelift protocol, and it is not focused ultrasound. How the two radiofrequency platforms differ is set out in Thermage FLX vs Volnewmer.
Where laxity sits deeper, along the jawline and under the chin, focused ultrasound reaches the deeper layer directly. Where the concern is skin quality and fine crêpiness, broad dermal heating is often the better fit. In lean or hollow faces, heat placed into fat that is not the target can make the face look more hollow; hollowing after Ultherapy, HIFU or Thermage is a recognised risk, which is why Dr Sin Yong does not prefer HIFU-type treatments for lean patients and uses the VF Lift – Vertical Facelift on Volnewmer instead. For puffier or heavier faces, he generally uses Time Freeze Laser LCLR®. His fuller comparison is on Ultherapy vs VF Lift vs Time Freeze.
“The question is not ultrasound or radiofrequency. It is where the laxity sits, and how much fat the face can afford to lose.”
Dr Sin YongOn choosing a tightening treatment
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Neither has been shown to be better overall. Two small randomised trials comparing microfocused ultrasound with monopolar radiofrequency found no significant difference in laxity improvement; in one, ultrasound was more painful.
In a neck trial, microfocused ultrasound was more painful than monopolar radiofrequency. Comfort varies with settings, area and the individual.
Hollowing after Ultherapy, HIFU or Thermage is a recognised risk, particularly in lean faces where heat reaches fat that is not the target. This is why the plan depends on how much facial fat you have.
Yes. Dr Sin Yong performs Ultherapy Prime and Thermage FLX personally. He also uses the VF Lift – Vertical Facelift on Volnewmer for lean or hollow faces and Time Freeze Laser LCLR® for puffier faces, and the assessment decides which fits.
US FDA 510(k) K260618 — Ulthera System (Merz), 2026: indicated to lift the eyebrow, lift lax submental and neck tissue, improve lines and wrinkles of the décolleté, and improve skin laxity on the abdomen, arms and knees. source
US FDA 510(k) summary K170758 — Thermage FLX (Solta Medical), 2017: 6.78 MHz; indications include non-invasive treatment of wrinkles and periorbital wrinkles. source
Alhaddad M, et al. Randomised split-face comparison of monopolar radiofrequency and microfocused ultrasound with visualisation for laxity (n=20). Dermatol Surg. 2019;45(1):131-139. doi:10.1097/DSS.0000000000001653. source
Jones IT, et al. Subsurface monopolar radiofrequency versus microfocused ultrasound with visualisation for neck laxity (n=20). Dermatol Surg. 2017;43(12):1441-1447. doi:10.1097/DSS.0000000000001216. source
Amiri M, et al. Microfocused ultrasound with visualization (MFU-V) effectiveness and safety: a systematic review and meta-analysis. Aesthet Surg J. 2025;45(3):NP86-NP94. doi:10.1093/asj/sjae228. source
Oni G, et al. Evaluation of microfocused ultrasound with visualisation for lower-face laxity (n=93 evaluated). Aesthet Surg J. 2014;34(7):1099-1110. doi:10.1177/1090820X14541956. source
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