What changed on 30 October 2026: added a section on when Juvelook is not the right choice, a questions-to-ask checklist and two FAQs; rewrote the opening; plainer wording in four paragraphs.
Juvelook Singapore in brief: Juvelook is a PDLLA collagen stimulator used for skin quality and fine texture. Dr Sin Yong can use it, including under the eyes, but he prefers energy-based treatment: FSX Laser for the skin, and the Restore arm of the VF Lift for hollow areas.
Published 9 October 2026 · Reviewed by Dr Sin Yong
Juvelook is a collagen-stimulating injectable made by VAIM in Korea. Each vial combines poly-D,L-lactic acid (PDLLA) microspheres with non-cross-linked hyaluronic acid. It sits between a skin booster and a volumising filler: the hyaluronic acid gives hydration on the day, and the PDLLA prompts the skin to lay down its own collagen over the following months. Dr Sin Yong offers Juvelook on Orchard Road, and also manages excess Juvelook placed elsewhere.
Short answerJuvelook is PDLLA plus hyaluronic acid: a 50 mg vial contains 42.5 mg PDLLA and 7.5 mg hyaluronic acid, and the larger Juvelook Volume (Lenisna) 200 mg vial contains 170 mg PDLLA and 30 mg hyaluronic acid, according to the manufacturer. Its particles are smaller, rounder and more porous than Sculptra’s PLLA flakes. Hyaluronidase dissolves its hyaluronic acid but not the PDLLA. Evidence so far is from small studies.
Dr Sin Yong prefers energy-based treatment for almost every concern that injectables are used for: FSX Laser for the skin, and the VF Lift for lifting and hollow areas. It adds no product, so there is no injected material to cause pillow face, migration or lumps. Where an injectable is the right choice, he says so and explains why.
Juvelook suits skin quality and fine lines; Juvelook Volume, sold internationally as Lenisna, has more PDLLA per vial for volume. Dr Sin Yong first decides whether the problem is skin quality, volume or laxity, because sagging is a lifting problem. Juvelook is an injectable collagen stimulator that its manufacturer, VAIM, classifies as a disposable medical device for the temporary improvement of facial wrinkles in adults. It is a powder of poly-D,L-lactic acid (PDLLA) microspheres, reconstituted before injection, carried in non-cross-linked hyaluronic acid rather than the carboxymethylcellulose used in Sculptra.
Juvelook, Juvelook Volume and Sculptra compared
Juvelook
Juvelook Volume / Lenisna
Sculptra
Polymer
Poly-D,L-lactic acid (PDLLA)
Poly-D,L-lactic acid (PDLLA)
Poly-L-lactic acid (PLLA)
Per vial
42.5 mg PDLLA + 7.5 mg HA
170 mg PDLLA + 30 mg HA
PLLA with carboxymethylcellulose and mannitol
Polymer structure
Amorphous
Amorphous
Semi-crystalline
Particle shape
Spherical, partly porous, ~30 µm
Spherical
Irregular sheet-like flakes, ~50 µm
Hyaluronidase
Dissolves the HA only
Dissolves the HA only
No effect
Typical use
Skin quality, fine lines, texture
Deeper volume and contour
Gradual volume through collagen
Particle data come from a 2025 laboratory comparison using electron microscopy (Su, Polymers 2025). It found Juvelook’s particles round with porous structures, with a mean size of about 30 µm. Sculptra’s particles were sheet-like and about 50 µm. A 2024 review discusses the difference in structure: amorphous (unordered) PDLLA against semi-crystalline (partly ordered) PLLA (Lee, Polymers 2024). How those physical differences translate into results in people has not been tested head to head.
Juvelook is planned for skin quality first; volume is a different decision.
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Juvelook, Sculptra or a skin booster?
A skin booster such as Profhilo or a polynucleotide places hydrating or regenerative material into the skin and is not designed to build volume. Sculptra is a volumising collagen stimulator given as a course, with no product volume on the day. Juvelook sits between them: its hyaluronic acid gives some hydration immediately, and its PDLLA works on collagen over months. Juvelook Volume carries more PDLLA and is used where structure, rather than surface quality, is the aim. Which fits depends on whether the concern is the skin, the volume beneath it, or both; see collagen biostimulators and Profhilo vs Rejuran.
Illustrative image — not a patient.
How Dr Sin Yong uses Juvelook
He starts by deciding whether the problem is skin quality, volume or laxity. Juvelook answers only the first two, and sagging is a lifting problem. He asks what has been injected before. Collagen stimulators and hyaluronic acid layered over several years are a common reason faces look heavy. Placement, dilution and the number of sessions are set after examination; this site does not publish session counts. He also manages the other side of the product: excess or clustered Juvelook placed elsewhere, including under the eye. For this he uses the Sculpting mode of Time Freeze Laser LCLR®, built to target the excess.
“Juvelook is a skin-quality tool first. If the real problem is sagging, more product is the wrong answer.”
Dr Sin YongOn choosing Juvelook
When Juvelook is not the right choice
Juvelook is a skin-quality tool first, so part of the assessment is deciding when it should wait or when another route fits better.
Pregnancy and breastfeeding. Collagen stimulators are deferred until afterwards.
Infection or inflammation in the area, including an acne flare or a cold sore: treatment waits until the skin has settled.
Allergy to a component, or a tendency to keloid or raised scarring. These are discussed first and can rule it out.
Sagging as the main concern. Juvelook answers skin quality and volume, not laxity, and more product is the wrong answer to a lifting problem.
Earlier filler or collagen stimulator of unknown type. It is assessed, with ultrasound where needed, before anything new is added.
Wanting a result that can be fully reversed. Hyaluronidase dissolves the hyaluronic acid carrier but not the PDLLA.
Where the examination shows heavy skin excess that no injectable can lift, a surgical opinion is advised, and a red, hot or painful lump after any injection needs a doctor the same day.
What the evidence shows
The published evidence is early and small. A prospective case series followed 20 patients treated for nasolabial folds, the lines from nose to mouth. It reported improvement on a global aesthetic scale at three months, and no nodules or granulomas (Yi, J Craniofac Surg 2026). A study of PDLLA in the tear trough of Korean women reported improvement on the Hirmand classification, without severe complications (Wan, J Cosmet Dermatol 2025). No randomised trial comparing Juvelook with Sculptra or with hyaluronic acid filler has been published. Much of the work comes from one research group.
Illustrative image — not a patient.
Risks to know
Swelling, bruising and tenderness are expected. Nodules (small lumps) can occur with any collagen stimulator. A case report described non-inflammatory nodules three weeks after PDLLA in the tear trough. They resolved after treatment with an energy-based device (Seo, J Cosmet Dermatol 2025). As with any injectable, filler entering a blood vessel is the serious risk. In 2026, an expert consensus was published on safe injection technique with the higher-concentration product, and on managing visual complications (Lau, J Craniofac Surg 2026). Vision change or eye pain after an injection: call 995 now.
Lumps after collagen stimulators are assessed with ultrasound before anything is done, but a red, hot or painful lump needs a doctor the same day; if no doctor can see you today, A&E.
Questions to ask before Juvelook in Singapore
These questions help you understand the plan before a collagen stimulator is injected.
Who examines my face, and who performs the injections?
Is Juvelook or Juvelook Volume proposed, and why that rather than a skin booster or Sculptra?
What can it not do for me, especially if my concern is sagging?
What are the risks, including nodules, and how would a lump be assessed?
What aftercare is advised, and how do I reach the doctor for a review?
Which alternatives, including no injection, were considered, given that PDLLA cannot be dissolved?
Excess or lumpy Juvelook
Hyaluronidase dissolves Juvelook’s hyaluronic acid carrier but not the PDLLA. A firm or lumpy area is assessed with ultrasound to see where the material sits, how deep, and whether other fillers are also present. Dr Sin Yong’s approach to excess collagen-stimulator material, including under the eye, is set out on lumps after Sculptra, Radiesse, Ellansé or Juvelook.
1. MessageWhatsApp +65 8023 7170 with what is bothering you. A reply comes from the clinic, not a bot.
2. AssessmentDr Sin Yong examines you himself on Orchard Road, with ultrasound where earlier filler is involved.
3. A plan in writingWhat he would do, what he would not, the fee factors, and the option of no treatment.
Every treatment is performed by Dr Sin Yong personally. Singapore Medical Council registered · invited to share his clinical expertise internationally as a Key Opinion Leader for CLASSYS, DEKA, HIRONIC, FOTONA, ALMA, LUTRONIC and ILOODA · HSA-registered devices · ultrasound-guided correction
No figure is published, because the plan has to come first. The fee follows what the examination finds: whether the concern is skin quality or volume, which areas are treated, how the product is diluted and placed, and whether earlier filler or collagen stimulator needs addressing before anything new is added. Dr Sin Yong sets out the fee factors in a written plan after the consultation.
Dr Sin Yong can use Juvelook under the eyes for skin quality and fine texture, but he prefers energy-based treatment there: FSX Laser for the skin, and the Restore arm of VF Lift – Vertical Facelift for hollow areas. Nodules can occur with any collagen stimulator. Hyaluronidase dissolves the hyaluronic acid carrier but not the PDLLA, so excess under the eye is managed with the Sculpting mode of Time Freeze Laser LCLR®.
Usually not. Get assessed first. Juvelook’s PDLLA cannot be dissolved, but it can still be treated without an incision: Dr Sin Yong maps it with ultrasound, treats an inflamed lump medically first, and treats nodules with the Sculpting mode of Time Freeze Laser LCLR®. Surgery leaves a scar, can leave a dent or injure a nerve, and cannot be undone. In his practice, almost every hard lump is treated without surgery. If yours is one of the few that needs surgery, you are told plainly, and why.
Swelling, redness, bruising and tenderness are expected, with small bumps at the injection points that settle as the skin recovers. Nodules can occur with any collagen stimulator, and a lump that lasts is scanned. A red, hot, painful or swollen lump needs a doctor the same day; if no doctor can see you today, A&E. Pale, dusky or mottled skin, or pain that is getting worse, needs urgent assessment by the doctor who injected you, or at A&E, now. A change in vision or eye pain after an injection: call 995 now.
No, though they are related. Both are lactic acid polymers that prompt the skin to make collagen. PDLLA microspheres are smaller, rounder and more porous than the PLLA flakes in other collagen stimulators, and in this product they are combined with non-cross-linked hyaluronic acid. Neither polymer is dissolved by hyaluronidase.
Lumps or clustered product are assessed first, usually with ultrasound, to see where the material sits. Hyaluronidase dissolves the hyaluronic acid component but not the PDLLA. For excess or clustered product, including under the eye, Dr Sin Yong uses the Sculpting mode of Time Freeze Laser LCLR®, built to target the excess.
Poly-D,L-lactic acid (PDLLA) microspheres with non-cross-linked hyaluronic acid. A 50 mg vial contains 42.5 mg PDLLA and 7.5 mg hyaluronic acid; Juvelook Volume (Lenisna) 200 mg contains 170 mg PDLLA and 30 mg hyaluronic acid, according to VAIM.
No. Both are collagen stimulators, but Juvelook uses amorphous PDLLA microspheres in hyaluronic acid, while Sculptra uses semi-crystalline PLLA particles in carboxymethylcellulose. Laboratory work found Juvelook’s particles smaller and spherical, Sculptra’s larger and sheet-like.
It sits between the two. Its hyaluronic acid gives some hydration on the day and its PDLLA works on collagen over months. Juvelook Volume carries more PDLLA and is used for structure.
Partly. Hyaluronidase dissolves the hyaluronic acid carrier but not the PDLLA. Excess Juvelook is assessed with ultrasound and managed as a collagen stimulator: Dr Sin Yong treats it with the Sculpting mode of Time Freeze Laser LCLR®, without an incision.
Yes, on Orchard Road, after an assessment of skin quality, volume and previous injectables. He also manages excess Juvelook placed elsewhere.
No duration can be promised. Collagen stimulators work through the body’s own collagen response, which varies between people, and published Juvelook studies have short follow-up.
References
VAIM Co., Ltd. Juvelook and Juvelook Volume (Lenisna) product information: composition and intended use. source
Su CY, et al. Physicochemical comparison of poly-D,L-lactic acid and poly-L-lactic acid injectable fillers. Polymers. 2025;18(1):84. doi:10.3390/polym18010084. source
Lee KWA, et al. Poly-d,l-lactic acid (PDLLA) application in dermatology: a literature review. Polymers. 2024;16(18):2583. doi:10.3390/polym16182583. source
Yi KH, et al. Poly-D,L-lactic acid with hyaluronic acid for nasolabial folds: a prospective case series (n=20). J Craniofac Surg. 2026. doi:10.1097/SCS.0000000000012819. source
Wan J, et al. Poly-D,L-lactic acid injection for the tear trough in Korean women. J Cosmet Dermatol. 2025;24(3):e70058. doi:10.1111/jocd.70058. source
Seo SB, Wan J, Yi KH. Non-inflammatory nodules after poly-D,L-lactic acid in the tear trough treated with monopolar radiofrequency: a case report. J Cosmet Dermatol. 2025;24(1):e16575. doi:10.1111/jocd.16575. source
Lau KHE, et al. Expert consensus on safe injection technique and management of visual complications with PDLLA-HA 200. J Craniofac Surg. 2026;37(5):1103-1109. doi:10.1097/SCS.0000000000012271. source
