Sculptra Singapore: Sculptra is injectable poly-L-lactic acid, a collagen stimulator that acts as a scaffold for the skin’s own collagen rather than filling on the day, and it cannot be dissolved. Dr Sin Yong scans earlier filler by ultrasound first, plans dilution and depth region by region, and under-corrects deliberately before each review.
Sculptra in Singapore: what it treats, and what it does not
Treats
Gradual volume loss of the cheeks, temples and jawline
Thin faces that look tired rather than dropped
Skin quality of the neck, décolleté and arms
Hollowing after weight loss
Not the right tool for
A face that needs lifting rather than volume
Thin skin under the eyes
Faces already heavy from earlier filler
Anyone unwilling to wait months for the result
Sessions, interval, downtime and review
Sessions
Usually 2–3
Interval
4–6 weeks
Downtime
Swelling for days; massage for 5 days
Review
At 12 weeks
Typical figures for planning; the number for you is decided at the assessment, and results vary.
What decides the fee for sculptra in Singapore
Number of vials and areas
Number of sessions
Whether earlier filler needs mapping or correction first
Fees are given in writing after the assessment: how we quote.
What Dr Sin Yong checks first
Sculptra builds collagen slowly, so dilution, depth and restraint matter more than the vial count. Most of the Sculptra lumps I correct from elsewhere came from placement and volume, not the product. I say no to Sculptra in a face that needs lifting; adding volume to a dropped face makes it heavier.
A flat or hollow forehead is assessed on its own terms: see forehead fillers.
Sculptra Singapore in brief: Sculptra treatment in Singapore uses poly-L-lactic acid (PLLA), called 童颜针 in Chinese: a collagen stimulator that works gradually as your skin builds collagen around it, not a filler that adds volume on the day. It cannot be dissolved, so it is placed conservatively after an ultrasound scan.
Dr Sin Yong · MBBS (NUS) · MRCS (Edin) · MSc Aesthetic Medicine with Distinction (Queen Mary, London) · MSc Practical Dermatology (Cardiff) · Global Key Opinion Leader
Sculptra is injectable poly-L-lactic acid. It adds no lasting volume of its own; it is a scaffold the skin builds collagen around over months, and it cannot be dissolved. It is assessed and placed by Dr Sin Yong at the clinic on Orchard Road, Singapore.
Sculptra Singapore · Dr Sin Yong, Orchard Road
Collagen over months. Assessed before any vial.
Gradual collagen
Does not dissolve
Lump risk explained
Doctor-injected
Illustrative, not a patient. Every treatment is performed by Dr Sin Yong after an in-person assessment.
Sculptra's poly-L-lactic acid prompts the skin to build collagen over months, and it cannot be dissolved. Dr Sin Yong assesses face volume and lump risk in person first, uses it where gradual support suits, and treats Sculptra lumps from elsewhere with the Sculpting mode of Time Freeze Laser LCLR®.
Lean, thin or nodule-prone faces are steered to reversible options; suitable faces are planned by zone.
and place deepDilute
Properly diluted product placed in the right layer is what keeps nodules rare.
over monthsReview
Collagen builds slowly, so the face is reviewed before any further vial is considered.
Suitability is decided at an in-person assessment. No prices are quoted on this page; fees are given in writing after the assessment. Images and video are illustrative, not patients.
Sculptra is injectable poly-L-lactic acid, a collagen biostimulator rather than a filler. It adds little volume on the day; the change builds gradually as the skin lays down new collagen. In Singapore its cost depends on the assessment, how much product is planned and how treatment is staged, and it cannot be dissolved once placed.
What Sculptra is: poly-L-lactic acid, a scaffold, not a filler
Sculptra is poly-L-lactic acid (PLLA), a biodegradable synthetic polymer manufactured by Galderma and used in dissolvable sutures and orthopaedic implants for decades. For aesthetic use it is supplied as a sterile powder of microparticles, reconstituted with sterile water before injection and placed in the deeper layers of the skin or just beneath them. It received US FDA approval in 2004 for HIV-associated facial lipoatrophy and in 2009 for nasolabial fold contour deficiencies.
Proportions are assessed from the front and in profile. Illustrative image, not a patient.
It is not a filler in the ordinary sense. A hyaluronic acid filler is a gel that occupies space the moment it is placed. Poly-L-lactic acid occupies very little space of its own. Fibroblasts treat the particles as a scaffold and lay down new type I collagen around them gradually, while the particles slowly break down by hydrolysis. A 2014 review of its composition and mechanism, in the Journal of Drugs in Dermatology, describes this sequence: a controlled tissue response around the microparticles, new collagen, and a gradual change as the particles degrade. What remains is your own collagen, not resident product. That distinction decides the timing of the result, the areas it suits, and what can be done if it goes wrong.
“"Sculptra only tightens." It doesn't. Collagen is tissue. It takes up space.”
Dr Sin YongOn what collagen stimulators actually do
Why the first week is not the result
The fullness visible straight after treatment is almost entirely the water it was mixed with, plus the swelling that follows any injection. Both settle, and the face often looks much as it did before. This is normal, and it is the point at which people who were not warned decide the treatment has failed. The real change is slower: collagen is produced gradually, so the product cannot be judged on the day, and it is the wrong choice for anyone who needs a change before a near event. Because the response continues after the appointment, placing enough on the day to see a result is the commonest route to too much later, and too much cannot be taken back.
Illustrative. Poly-L-lactic acid is supplied as a dry powder and reconstituted with sterile water before it is placed; the fullness seen on the day is mostly that water.
Illustrative diagram, not to scale.Use this diagram on your site
Free to use with credit and a link. Copy this code:
Who it suits, and who should not have it
It suits diffuse, structural volume loss: the overall deflation of the mid-face, temples and lower face that comes with age or after significant weight loss, in a patient who can wait for a gradual result and understands it cannot be reversed. It is particularly logical where the face reads tired rather than lined. Thin faces, full faces, age and the under-eye exclusion are covered under am I suitable for a biostimulator.
Who it suits, who should wait, who should not have it
Group
Typical situation
What usually happens
Tends to suit
Diffuse deflation of the mid-face, temples and lower face; a face that reads tired rather than lined; able to wait and attend review
Staged, conservative placement with reassessment
Should not have it
Known hypersensitivity to any component; a history of, or tendency to, keloid or hypertrophic scarring (both contraindications in the US FDA labelling)
Not used
Better to wait
Pregnancy or breastfeeding; active infection or inflammation in the area, including an acne flare or a cold sore
Deferred
Assessed first
Immune suppression or an active autoimmune condition; a bleeding tendency or blood-thinning medicines; earlier non-dissolvable or unknown filler in the area
Discussed carefully; earlier filler scanned first, which may rule it out
Poor candidates by expectation
A visible change needed before a near event; unable to return for review; uneasy with a result that cannot be reversed
Another option, or no treatment
Referred on
A jowl or loose jawline from laxity; lumps or heaviness from earlier filler
Focused ultrasound or VF Lift – Vertical Facelift assessment; ultrasound scan and filler correction
Where it is placed, and how it compares with CaHA, PCL and HA
Where it is placed, and where it is not
Sculptra is a collagen biostimulator, not a filler: it is placed as a dilute suspension and the body builds collagen around the particles over the following months. Because it cannot be dissolved and keeps building after the appointment, it goes only where the tissue is thick enough to hide a particle and where a gradual, diffuse change is wanted. The published consensus favours a more dilute suspension and deeper placement, on or near the bone, where the skin is thin, and allows a less dilute product in the deeper subcutaneous plane of the fuller cheek.
Where poly-L-lactic acid is placed, and where it is not
Thin, mobile skin shows every particle, and a nodule there cannot be dissolved; a reversible hyaluronic acid product is used instead
Not applicable
PLLA, CaHA, PCL and hyaluronic acid compared
Material
What it is
How it works
Can it be dissolved?
Where it is typically considered
PLLA (poly-L-lactic acid)
Microparticles reconstituted in sterile water
Prompts the body's own collagen gradually; little immediate volume
No
Diffuse volume loss in the temples, cheeks and jawline, placed in stages
CaHA (calcium hydroxylapatite)
Microspheres in a gel carrier
The gel gives immediate support; collagen forms around the spheres; also used diluted for skin quality
No
Support on bone, such as the jawline, chin and nose
PCL (polycaprolactone)
Microspheres in a gel carrier
Immediate correction from the gel, with collagen stimulation around the spheres
No
Contour and support on bone
Hyaluronic acid (HA)
Cross-linked gel
Fills and binds water to add volume straight away
Yes, with hyaluronidase
Areas where reversibility matters, such as the lips and under-eye
Which material suits you is an anatomical decision made at assessment, not a preference. The options are compared in more depth on collagen biostimulators in Singapore and collagen injection vs collagen biostimulator. For a single discrete temple hollow, hyaluronic acid is used at this practice because it can be dissolved.
Does Sculptra work? What studies of poly-L-lactic acid show
A 2024 systematic review of poly-L-lactic acid in facial aesthetics included 11 randomised controlled trials. Four showed increased dermal thickness and improved scores, with effects sustained for at least 25 months. Side effects were mild to moderate and included bruising, tenderness, swelling and nodules.
The same review judged five of the 11 trials to be at high risk of bias and rated the overall evidence as low quality, concluding that the reported effectiveness needs further study. A 2026 systematic review of collagen stimulators found them effective with mostly mild side effects, and asked for standardised technique and long-term safety data. These reviews support what is done before any vial is used: assessing whether gradual collagen support is what the face needs, and explaining that nodules are a known risk.
What it cannot do, and the alternatives
It does not lift. A jowl or a loose jawline is a laxity problem and belongs to focused ultrasound or the VF Lift – Vertical Facelift, Dr Sin Yong's radiofrequency protocol on Volnewmer, not to an injectable.
It does not shape a chin, a nose or a lip. Projection needs a product with form on the day.
It does not suit the lips, the tear troughs or fine superficial lines, areas that punish a non-dissolvable product placed close to the surface.
It does not give a change on the day, so it does not suit a near event.
It is not lifelong. Poly-L-lactic acid is broken down over time, and the skin returns to its own trajectory as the collagen it produced ages like the rest.
It cannot be dissolved
Hyaluronidase, the enzyme used to reverse hyaluronic acid filler, has no action on poly-L-lactic acid. If it is placed too superficially, in the wrong plane or in excess, the options are time, targeted treatment of any nodules, and in some cases procedural removal. None of those is equivalent to dissolving. Dr Sin Yong treats lasting nodules with the Sculpting mode of Time Freeze Laser LCLR®, without an incision.
Two myths we hear in clinic
“It only tightens skin.”
Collagen is tissue and takes up space, so it builds gradual volume rather than tightening.
“If the result is not right, it can be dissolved like hyaluronic acid filler.”
Hyaluronidase acts on hyaluronic acid only, so poly-L-lactic acid cannot be dissolved and is planned conservatively.
Risks and side effects
The common findings are those of any deep injectable: swelling, bruising, tenderness and temporary asymmetry while the water settles. Papules and nodules are the specific risk of this product: the US pivotal trial reported them in 17.2% of patients, typically appearing months after treatment and mostly resolving on their own. Dilution, depth of placement and post-treatment massage all influence that figure, which is why technique rather than brand is the variable that matters. The serious risks are the vascular ones that attend any product placed near facial vessels, which is why plane and anatomy matter more than the product.
Any lump that is growing is examined rather than massaged on faith, and one that is red, hot or painful needs a doctor the same day (A&E if no doctor can see you today); the lumps and nodules after poly-L-lactic acid page covers what is done. For migrated poly-L-lactic acid and other non-HA product, Dr Sin Yong uses the Sculpting mode of Time Freeze Laser LCLR®, which is built to target the excess, after mapping with ultrasound; see nodules vs migration and filler correction.
What to expect: before, on the day and recovery
Before you book
Tell the clinic about every previous filler or biostimulator, with dates and areas if you know them.
Declare pregnancy, breastfeeding, autoimmune conditions and any history of keloid scarring.
Mention blood thinners, aspirin, fish oil or supplements that increase bruising.
Avoid fresh sun exposure, pause strong skincare actives as advised, and bring photos of your face over the years.
On the day
Previous filler is mapped with ultrasound first. Dilution and plane are then set region by region, the product is placed, and the treated areas are massaged as instructed. The day in sequence, including the massage rules, is set out under what to expect at a biostimulator visit.
What recovery looks like
The sequence below describes phases, not a timetable: how quickly each passes depends on the area and the person, and is discussed at consultation.
Immediately after. Fullness from the injected water and swelling, with tenderness and possibly bruising; this early volume is not the result.
The first evening. Massage the treated areas as instructed and avoid pressure, heat and alcohol; a cool compress limits swelling.
The following days. The water is absorbed and the face returns almost to its starting point; bruising fades and temporary asymmetry settles.
As the skin settles. Collagen builds gradually around the microparticles over the following weeks and months, so the change appears slowly.
Follow-up. Any further placement is decided at review from what the skin has produced, and any late papule or nodule is assessed.
The cost of Sculptra in Singapore depends on how much product your face needs and how that is staged, which can only be judged at assessment. There is no fixed number of vials for a face, and a figure quoted before an examination would describe a plan that does not yet exist. The extent of the volume loss matters most: diffuse deflation across the temples, mid-face and lower face needs more than a single area. Face size, skin thickness and the dilution chosen for each region also change how much is used, and earlier filler may need to be scanned and sometimes dissolved first.
Proportions are assessed from the front and in profile. Illustrative image, not a patient.
Staging is the other variable. Because poly-L-lactic acid keeps building collagen after the appointment and cannot be dissolved, Dr Sin Yong under-corrects deliberately and decides any further placement at review. The number of vials is therefore an outcome of the plan rather than something chosen in advance. Prices are discussed at consultation rather than published, in line with Singapore's rules on medical advertising. What sets the fee, vial by vial, is on cost factors, and how quotes work is on how we quote.
How Dr Sin Yong places it, and why he scans first
Poly-L-lactic acid is a planning product more than an injecting product. The decisions that determine the result are made before the needle: how much water the powder is reconstituted with, which plane each region is placed in, and how much is placed at a first visit against how much is left for reassessment. Dr Sin Yong plans dilution and plane region by region, because the temple, the mid-face and the pre-jowl area are different depths and different tissues. He under-corrects deliberately, reviews as the collagen response develops, and decides any further placement from what the skin has actually produced rather than from a pre-sold plan.
Noticed lumps or heaviness? Scan before you add
A face that has been injected more than once often arrives with a complaint that sounds like it needs more product: a heaviness in the lower face, a fullness under the eyes, a lump months after the last visit. In Dr Sin Yong's experience the problem is more often what is already there, and the answer is subtraction, not addition. So before any further placement, he scans. High-frequency ultrasound shows what material is in the tissue, how deep it is, whether it has migrated, and whether a lump is poly-L-lactic acid, old hyaluronic acid filler, a cyst or scar. If the scan shows that less is what you need, that is filler correction, a different procedure. If it shows a clean field, placement can go ahead. Nothing is added to a face that has not been looked beneath.
Related on this site
If a lump forms after treatment, the guide to hard filler lumps explains how it is assessed.
Sculptra: sessions, downtime and how long it lasts
Sculptra Singapore at a glance
How many sessions
Usually 2–3 sessions, 4–6 weeks apart, each with a review before the next vial.
Downtime
Swelling for 2–3 days; bruising for up to a week; massage instructions for 5 days.
How long it lasts
Collagen builds over 3–6 months and results are commonly reviewed at 2 years; the product cannot be dissolved.
Figures are typical ranges from Dr Sin Yong's practice and the published literature; your plan, including the number of sessions, is set after the assessment and may differ. Fees are given in writing after the assessment: see how we quote.
Sculptra correction
Had Sculptra elsewhere and something is not right?
Lumps, nodules or an overfilled look after Sculptra can be assessed without committing to treatment. Sculptra cannot be dissolved with hyaluronidase, so the first step is to see exactly what is there. More on Sculptra nodules and lumps and Sculptra gone wrong.
Dr Sin Yong examines you himselfHe looks at and feels the area, and scans it with ultrasound where earlier filler is involved.
You see what is thereHe shows you on the screen what the scan finds and where it sits.
You decideHe sets out the options: treat, monitor or leave alone. Nothing is done on the day unless you choose it.
Who you will see: Dr Sin Yong. He performs every assessment and treatment himself.
Most people describe pressure and stinging at each injection point rather than sharp pain. Poly-L-lactic acid is reconstituted with water before use, and numbing cream can be applied first. How it feels depends on the area, the depth and individual sensitivity, and areas close to bone tend to be more noticeable. Tell Dr Sin Yong at any point if it is uncomfortable, and the pace is adjusted.
Which areas of the face is Sculptra used for?+
Poly-L-lactic acid is used for diffuse volume loss rather than sharp contour: commonly the temples, the mid-face and the area in front of the jowl. Each region sits at a different depth, so dilution and plane are planned region by region. It is not used in the lips or under the eyes, where thin, mobile skin shows any particle and a nodule is more likely. Areas that need precise shape or reversibility are planned with other products.
Can Sculptra lift sagging skin?+
No. Poly-L-lactic acid builds collagen and gradual volume; it does not lift tissue that has descended. A jowl, a softened jawline or loose skin is a laxity problem, and adding volume to it can make the lower face heavier. Dr Sin Yong treats laxity first with the VF Lift – Vertical Facelift, his radiofrequency protocol on Volnewmer, and Time Freeze Laser LCLR®, and uses a collagen stimulator only where real volume loss remains.
What does a Sculptra treatment do?+
A Sculptra treatment places poly-L-lactic acid in the deeper layers of the face, where it acts as a scaffold that prompts the skin to lay down its own collagen. The change builds gradually over months rather than on the day, which is why treatment is staged and reviewed. Sculptra does not relax muscles or tighten skin with heat; it is considered where support and volume have thinned.
How is a Sculptra treatment different from a hyaluronic acid filler?+
A Sculptra treatment differs from a hyaluronic acid filler in how it works and whether it can be reversed. Hyaluronic acid filler adds volume on the day and can be dissolved with hyaluronidase. Sculptra adds little volume at first, works through the collagen the skin builds around it, and cannot be dissolved, so it is placed conservatively after an ultrasound scan of the area.
How do I check that a Sculptra treatment in Singapore uses an approved product?+
In Singapore, medical devices, which include most aesthetic lasers, energy devices and injectable fillers, must be registered with the Health Sciences Authority (HSA) before they can be supplied; only the lowest-risk class A devices are exempt. Ask which injectable will be used and check it on HSA’s medical device register, and check that the clinic holds an MOH licence.
Who is Sculptra suitable for in Singapore?+
Sculptra suits diffuse, structural volume loss: the overall deflation of the mid-face, temples and lower face that comes with age or after significant weight loss. It fits someone who can wait for a gradual change, can attend review and accepts that it cannot be dissolved. It is not used with a keloid tendency or a known hypersensitivity, and it is deferred in pregnancy or with infection in the area. A loose jawline is assessed for lifting instead.
Do I need surgery to remove Sculptra?+
Usually not. Get assessed first. Sculptra cannot be dissolved, but it can still be treated without an incision: Dr Sin Yong maps it with ultrasound, treats an inflamed lump medically first, and treats nodules with the Sculpting mode of Time Freeze Laser LCLR®. Surgery leaves a scar, can leave a dent or injure a nerve, and cannot be undone. In Dr Sin Yong’s practice, almost every hard lump is treated without surgery. If yours is one of the few that needs surgery, you are told plainly, and why.
Is a PLLA biostimulator a filler?+
Not in the usual sense. A filler is a gel that occupies space the day it is placed. Sculptra is poly-L-lactic acid microparticles that occupy very little space themselves; they prompt the skin to build collagen around them gradually. The fullness seen on the day is mostly the water it was mixed with.
Can Sculptra be dissolved?+
No. Hyaluronidase breaks down hyaluronic acid only and has no effect on poly-L-lactic acid. Problems are managed with time, targeted treatment of nodules and, in some cases, procedural options. This is the single most important fact to understand before choosing it. Dr Sin Yong treats lasting nodules with the Sculpting mode of Time Freeze Laser LCLR®, without an incision.
How long does Sculptra take to work?+
Gradually. The injected water and swelling settle first, and the collagen response builds afterwards, so the change appears slowly. If you need a visible change before a near event, this is the wrong product and you will be told so.
Does Sculptra cause lumps?+
Papules or nodules were reported in 17.2% of patients in the US pivotal trial, typically months after treatment and mostly resolving on their own. Dilution, depth and aftercare influence the risk. A lump that is growing should be examined, not massaged on faith. One that is red, hot or painful needs a doctor the same day; if no doctor can see you today, A&E.
How much Sculptra is needed, and what decides it?+
There is no fixed number of vials for a face. The amount follows the extent of volume loss, how many regions are involved, face size, skin thickness and the dilution chosen for each region. Earlier filler may need scanning, and sometimes dissolving, first. Because poly-L-lactic acid cannot be dissolved, Dr Sin Yong under-corrects and decides further placement at review.
Can Sculptra be used under the eyes or in the lips?+
These are the areas where a non-dissolvable product placed near the surface is most likely to cause trouble, and they are not where Dr Sin Yong uses it. A reversible hyaluronic acid product is the more defensible choice there.
Who is the right doctor for Sculptra in Singapore, and what should I check?+
No register ranks doctors, so check credentials rather than claims. Confirm the doctor is on the Singapore Medical Council register and the clinic is licensed under the Healthcare Services Act. Ask who assesses and injects, whether existing filler is scanned first, and how dilution and plane are planned. Dr Sin Yong holds MBBS (NUS), MRCS (Edinburgh), MSc Aesthetic Medicine (University of London) and MSc Practical Dermatology (Cardiff).
How much does Sculptra cost in Singapore?+
The cost depends on the areas treated, the amount of product your anatomy calls for, how the plan is staged, and whether it is combined with another treatment. Because the result builds after you leave and cannot be reversed, a written quote is given at consultation after assessment, and the consultation decides whether it is advised at all.
Is Sculptra the same as 童颜针?+
童颜针 (literally “youthful-face injection”) is a Chinese nickname for poly-L-lactic acid collagen stimulators such as Sculptra. The name is marketing shorthand and does not describe a result.
Is Sculptra worth the money?+
It depends on what you want it to do. Sculptra suits gradual, diffuse volume loss, such as at the temples or the sides of the cheeks, in someone happy to wait for collagen to build over weeks. It is a poor choice for a sharp, instant change such as lip or nose shaping, and it cannot be dissolved, so it should be placed by a doctor who knows the anatomy and can manage lumps. The assessment decides whether it suits you at all.
Why do some doctors not like Sculptra?+
Mainly because it is unforgiving. Poly-L-lactic acid cannot be dissolved the way hyaluronic acid can, and if it is mixed, placed or massaged poorly it can form papules or nodules that take time to manage. Its effect also builds slowly, which makes it harder to judge on the day. Where lumps have formed, Dr Sin Yong maps them with ultrasound and uses the Sculpting mode of Time Freeze Laser LCLR® to target the excess.
Is Sculptra better than fillers?+
Not better, different. A hyaluronic acid filler adds volume on the day and can be dissolved if needed. Sculptra is a poly-L-lactic acid collagen stimulator: its effect builds gradually over weeks as your own collagen forms, and it cannot be dissolved. Sculptra suits broad, gradual volume loss; hyaluronic acid suits defined shaping. Some faces need neither.
How much is 3 sessions of Sculptra?+
There is no standard three-session package here. How many vials and visits are needed depends on how much volume has been lost, the areas treated and how your skin responds, so it is planned after assessment. The fee for that plan is given to you in writing after the consultation.
In Singapore, Sculptra patients who already have hollowing from a thin face, a history of nodules from other stimulators, or a wish to keep the option of dissolving later are usually steered to other treatments. Because poly-L-lactic acid cannot be dissolved, Dr Sin Yong assesses the face in person and discusses the lump risk before any Sculptra is planned.
Both are polylactic acid collagen stimulators, but they sit at different depths and do different jobs. Sculptra is placed deep, over bone or in the deep fat, to rebuild structural support in temples, cheeks and the jawline. Juvelook is PDLLA with hyaluronic acid placed in the skin itself for pores, fine lines and acne scar texture. Dr Sin Yong decides by whether the problem is support or skin quality; neither can be dissolved, so the assessment comes first.
Vleggaar D, Fitzgerald R, Lorenc ZP. Composition and mechanism of action of poly-L-lactic acid in soft tissue augmentation. Journal of Drugs in Dermatology 2014;13(4 Suppl):s29-s31. source
Consensus recommendations on the use of injectable poly-L-lactic acid for facial and nonfacial volumization (Vleggaar D, Fitzgerald R, Lorenc ZP et al.). Journal of Drugs in Dermatology, 2014. pubmed.ncbi.nlm.nih.gov
US Food and Drug Administration. SCULPTRA® Aesthetic (injectable poly-L-lactic acid): summary of safety and effectiveness and labelling, P030050/S002, 2009. source
Wortsman X. Identification and complications of cosmetic fillers: sonography first. Journal of Ultrasound in Medicine 2015;34(7):1163-1172. source
Signori R, Barbosa AP, Cezar-Dos-Santos F, Carbone AC, Ventura S, Nobre BBS, et al. Efficacy and Safety of Poly-l-Lactic Acid in Facial Aesthetics: A Systematic Review. Polymers, 2024. doi.org
Ferreira ACM, Silva LR, Espasandin I, Sant'Anna JF, Mourão CA, Tedesco AD, et al. Efficacy, Durability, and Safety of Collagen Biostimulators Based on Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA) in the Face: A Systematic Review. Aesthetic Plastic Surgery, 2026. doi.org
Medically reviewed by Dr Sin Yong, MBBS (NUS), MRCS (Edinburgh) · Last updated 5 November 2026 · Editorial policy
Where Dr Sin Yong consults: 9 Scotts Road, Pacific Plaza #12-01, Singapore 228210 · Orchard MRT · Mon–Fri 10am–8pm, Sat 11am–3pm · WhatsApp +65 8023 7170 · Getting here · How fees are quoted
Assessed before it is injected
Whether a non-dissolvable biostimulator is the right answer depends on the anatomy, on what has been injected before, and on how much time you have. Dr Sin Yong assesses that first.
