Medically reviewed by Dr Sin Yong · Last reviewed · 7 min read · Jump to questions
Published 20 October 2026 · Reviewed by Dr Sin Yong

Profhilo aftercare is mostly about leaving the raised bumps alone. Profhilo is placed as a small deposit at each Bio Aesthetic Point and left to spread, so a bleb at each point straight afterwards is the expected appearance of a correct deposit, not a complication. Avoid make-up, heat, alcohol and exercise on the first day, do not massage the points, and report pain that increases or skin that changes colour.
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Profhilo aftercare is mostly patience with the blebs: the small raised points at each Bio Aesthetic Point are expected and flatten as the hyaluronic acid spreads on its own, so they are not massaged. Make-up, exercise, saunas and alcohol wait at first, because heat adds to swelling and bruising. Increasing pain, white or dusky skin, spreading redness or a growing bump is reported.
Bumps after Profhilo are expected. The product is not spread across the face the way a mesotherapy cocktail is; it is placed as a discrete deposit at each of the Bio Aesthetic Points, five per side at the zygomatic protrusion, the nasal base, the tragus, the chin and the mandibular angle. Those points were chosen for vascular safety and because an uncrosslinked, low-viscosity hyaluronic acid diffuses through the subcutaneous layer from the point of deposit. A raised wheal at each point straight afterwards is what a correct deposit looks like while the material sits before dispersing.

Do not massage the bumps unless you have been told to. The product spreads on its own as the tissue takes it up, and pressing a deposit before it has dispersed does not speed that up; it pushes material sideways and adds bruising. Dr Sin Yong places a modified BAP, keeping the manufacturer's points as the safety frame and adding placement according to the individual face, so the written aftercare for your visit names any point where a different instruction applies. The BAP technique page explains the pattern; the Profhilo page explains what the treatment is directed at and what it cannot do.
On the first day, keep the points clean and leave them alone. Cleanse gently in the evening with lukewarm water and a mild cleanser, pat dry, and use a plain moisturiser if the skin feels tight. Avoid make-up over the injection points on the first day, so that bacteria are not carried into entry points that have not yet closed; a tinted sunscreen over intact skin away from the points is reasonable if you must go out.
Avoid heat, alcohol and exercise for the rest of the day. Hot showers on the face, saunas, steam rooms, hot yoga and alcohol widen blood vessels and prolong swelling and bruising, and hard exercise raises blood pressure and does the same. A cool compress held lightly against a tender point for a short spell eases it; do not press. Paracetamol is reasonable if you need it; avoid anti-inflammatory painkillers unless the clinic has said otherwise, as they can increase bruising. Sleep face-up with the head slightly raised while the points are tender, because the tragus and mandibular angle points sit exactly where a side-sleeper presses into the pillow.
“A bleb at each point is what a correct Profhilo deposit looks like. It is the product sitting where it was put, before it spreads.”
Dr Sin YongOn the bumps after Profhilo
Make-up can go on once the entry points have closed, over intact skin, applied lightly without rubbing and removed gently. If a point is still raised or bruised, cover it with a light concealer rather than foundation worked in with a brush. Normal skincare can usually restart once the points have closed; pause retinoids and exfoliating acids until the skin feels ordinary if it is sensitive, and do not start any new active product while the points are still settling, because a reaction is harder to interpret then.
Light exercise such as walking is fine once the first day is over. Hard exercise, hot classes, saunas and steam are better left until the bumps have flattened and any bruising has stopped spreading; treat it as a question of heat and blood flow rather than of effort. Facials, facial massage, gua sha and at-home devices over the treated points wait until the skin is ordinary again, and any energy-based treatment over the same area is spaced as set out in your plan. Daily sunscreen continues throughout, and a bruise is kept covered or under sunscreen, because a bruise exposed to the sun can leave a brown mark in Fitzpatrick III to V skin.
| Phase | What is usual | What to do |
|---|---|---|
| Straight after | A bleb at each point; mild redness | Leave the points alone; no make-up over them |
| The first evening | Blebs beginning to flatten; tenderness at the points | Gentle cleanse; no heat, alcohol or exercise; sleep face-up |
| The following days | Bruising and tenderness settling; skin looks ordinary once the blebs have dispersed | Make-up over intact skin; light exercise; sunscreen daily; no massage, facials or saunas yet |
| As the skin settles | Hydration and bounce develop gradually, not on the day | Simple routine; judge the change at review |
Normal after Profhilo is a bleb at each point that flattens as the hyaluronic acid spreads, mild redness, tenderness at the points, transient swelling, and bruising, which is more likely near the mandibular angle and the tragus where vessels run close to the surface. Pinpoint bruises can appear. The skin looks ordinary once the blebs have dispersed. These settle on their own and are covered on the skin booster aftercare page, which applies to Profhilo and to Rejuran alike.
Not normal is a bump that is getting larger rather than flattening, redness that is spreading with warmth, pain after the first day that is increasing rather than settling, or swelling that does not subside. A palpable nodule that persists after the points have otherwise settled is uncommon and is examined rather than massaged. Delayed inflammatory reactions to hyaluronic acid devices are described in the literature and are infrequent; they need review, not waiting.
Vascular events after Profhilo are rare, partly because the Bio Aesthetic Points were chosen for anatomy that is comparatively free of significant vessels, but low risk is not absence of risk. Skin turning white, dusky or net-like near a point, or pain that is severe and worsening, is time-critical and needs assessment the same day. Hyaluronidase, which dissolves hyaluronic acid, is kept on site wherever it is injected.
Message the clinic on WhatsApp during clinic hours if you notice any of the following:
Go straight to a hospital emergency department for any change in vision or swelling of the lips, tongue or throat with difficulty breathing, and do not wait for a message reply. The complication care page sets these signs out in full. Most messages after Profhilo turn out to be ordinary bruising or a slow-to-flatten point, and you will be told plainly whether what you describe sounds expected, needs to be seen, and how soon.
The review is timed in words rather than by a fixed calendar: once the blebs have dispersed, the bruising has gone and the skin has had time to respond, which is when hydration and bounce can be judged. Any second placement is decided at that review according to what the skin is doing, the area treated and what else is planned; no standard course is quoted here. If you had Profhilo elsewhere and something feels wrong, the same warning signs apply. The consultation process page describes how an assessment here works, and the flying after treatment page covers travel timing.
Every treatment is performed by Dr Sin Yong personally. Singapore Medical Council registered · invited to share his clinical expertise internationally for CLASSYS, DEKA, Fotona, Hironic and Ilooda.
Mention blood thinners, aspirin or fish oil before the visit; they make bruising at the points more likely. How consultations work.
WhatsApp Dr Sin Yong →or use the enquiry formThey flatten as the hyaluronic acid spreads through the tissue, usually quickly; the skin looks ordinary once they have dispersed. A bump that is getting larger rather than smaller, or one that persists after the others have settled, is examined rather than massaged.
Not over the injection points on the first day, so that bacteria are not carried into entry points that have not closed. Once the entry points have closed it can go on lightly over intact skin and be removed gently; a bruised or still-raised point is covered with a light concealer rather than worked over with a brush.
Not on the first day. Hard exercise raises blood pressure and saunas, steam and hot yoga raise skin temperature, and both add to swelling and bruising at the points. Walking is fine once the first day is over; hot classes and saunas wait until the bumps have flattened and bruising has stopped spreading.
No, unless you have been told to for a specific point. The product disperses on its own from each Bio Aesthetic Point; pressing a deposit before it has spread pushes material sideways and adds bruising. The written aftercare names any point where a different instruction applies.
The review is timed once the blebs have dispersed, the bruising has gone and the skin has had time to respond, because that is when hydration and bounce can be judged. Whether a second placement is appropriate, and when, is decided then from what the skin is doing; no standard course is quoted.
Efficacy and tolerance of an injectable medical device containing stable hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: a monocentric 16 weeks open-label evaluation. Clinical, Cosmetic and Investigational Dermatology (Sparavigna A, Tenconi B), 2016. source
Hybrid cooperative complex treatment is associated with reduced facial pore size in a pilot study. Scientific Reports (Koppert E, Zamin RZ, Lee S, Yi KH), 2026. source
About this page: written and medically reviewed by Dr Sin Yong, MBBS (NUS), MRCS (Edinburgh) · Last reviewed 20 October 2026 · Illustrative images only, not patients · Editorial policy
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