Acne · Explainer

Cortisone injection for acne in Singapore:
when a cyst is injected, the atrophy risk, and what else acne needs

Medically reviewed by Dr Sin Yong · Last reviewed · Jump to questions

Deep nodules on the back and shoulders are covered under back acne.

Uniform, itchy bumps are not a cortisone question; they may be fungal acne.

Main guide  Acne treatment Singapore — what it treats, who it suits, sessions, downtime and what decides the cost, by Dr Sin Yong.

For acne that is widespread rather than a single cyst, see doxycycline for acne.

Published 21 October 2026 · Reviewed by Dr Sin Yong

Illustrative image for cortisone injection for acne — not a patient

A cortisone injection for acne places a small amount of dilute corticosteroid, usually triamcinolone, directly into one inflamed nodule or cyst to calm the inflammation inside it. It treats that lesion only, carries a risk of a dent or pale patch at the site, and does nothing to stop new cysts forming. Availability is confirmed at consultation, after the skin has been examined.

Cortisone injection for acne vs keloid steroid injection: the same medicine, a different job

The same corticosteroid is used for acne cysts and for keloids, which is why the two are sometimes confused. The target, the aim and the way the course is run are different.

FeatureAcne cyst or noduleKeloid or hypertrophic scar
What is being treatedAcute inflammation inside one active lesionOveractive scar tissue that keeps laying down collagen
AimCalm one lesion sooner and reduce the inflammation that can lead to a scarSoften and flatten established scar tissue over a reviewed course
Concentration and volumeDilute, small, set for thin facial skinSet for dense scar tissue and adjusted to response
Usual patternAn occasional injection for a particular lesionA course, reviewed visit by visit
What it is combined withMedical acne treatment matched to severitySilicone, pressure, laser or other adjuvants
Main local riskDent from fat thinning, pale patchThinning or lightening of the surrounding skin

The keloid steroid injection page explains the scar course in detail. A point the two share is that dose and depth decide most of the risk, which is why both are a doctor's procedure after assessment, not something offered across a counter. Acne itself can also lead to keloids on the jaw, chest and shoulders in people who are prone to them, and those scars are assessed separately from the active acne.

Part of Acne & Scars →

Key facts
What is injected
A dilute corticosteroid, most often triamcinolone acetonide, placed into the centre of one inflamed nodule or cyst
What it does
Targets the inflammation inside that lesion; it does not treat the acne producing the cysts
When it is used
A large, tender, deep lesion, often one that is distressing or arrives before an important event
Main risk
Thinning of the fat beneath the site (a dent) or a pale patch, more likely with stronger concentrations and repeat injections
Not used for
Small surface pimples, comedones, an infected or pus-filled lesion that needs other care, or a site injected repeatedly
What else is needed
Medical acne treatment matched to severity, which is what is aimed at preventing the next cyst and the scar it leaves
On this page
  1. What is a cortisone injection for acne?
  2. Which lesions are injected, and which are not: the lesion-by-lesion decision
  3. Cortisone injection for acne vs keloid steroid injection: the same medicine, a different job
  4. Can a cortisone shot leave a dent? Atrophy and other side effects
  5. What else is needed besides the injection?
  6. Frequently Asked Questions
  7. Related
  8. Speak With Dr Sin Yong

What is a cortisone injection for acne?

A cystic or nodular acne lesion forms when a follicle ruptures deep in the dermis and the immune response walls off the spilled contents into a firm, tender lump. Because the inflammation sits millimetres below the surface, creams barely reach it, squeezing pushes it sideways, and it can be slow to settle on its own. The cystic and nodular acne page explains why these lesions hurt, persist and scar.

Illustrative image — What is a cortisone injection for acne?; not a patient
Illustrative image — not a patient.

A cortisone injection, also called an intralesional corticosteroid injection or cortisone shot, goes straight to that inflammation. After examination, a doctor uses a fine needle to place a small volume of dilute corticosteroid, most often triamcinolone acetonide, into the centre of the lesion. The corticosteroid suppresses the inflammatory signals inside the nodule, with the aim of settling pain and swelling sooner than they would settle on their own; the lump can take longer to flatten fully and a mark may remain. DermNet lists acne cysts among the conditions treated this way, and acne guidelines from the American Academy of Dermatology include intralesional corticosteroid as an adjunct in their good practice statements.

The word adjunct matters. An injection acts on one lesion, in one place, at one time. It has no effect on the oil glands, follicles and inflammation that produced it, so it is used alongside acne treatment, never instead of it. A person with one occasional deep spot and a person with a steady stream of new cysts are having very different conversations, even if both ask for the same injection.

Cortisone shots for acne cysts: what an injection does and does not do

A cortisone shot for acne is an injection of a dilute corticosteroid directly into a single inflamed nodule or cyst. It is used to settle an individual painful lesion quickly, for example a large cyst before an important event, by suppressing the inflammation inside it. It acts on that one lesion only.

It does not treat acne as a condition and does not stop new cysts forming, because it has no effect on follicular blockage, sebum or bacteria elsewhere in the skin. Its main risks are local: a small depression where the fat beneath the injection site thins, or a pale patch of skin, both more likely with stronger concentrations or repeated injections into the same spot. In darker skin, a pale patch can be particularly noticeable. Someone needing repeated injections for recurring cysts is really describing nodulocystic acne, the grade where early medical management matters most because it carries the greatest risk of scarring. Whether an individual cyst is better managed with an injection or within a wider medical plan is decided at assessment.

Which lesions are injected, and which are not: the lesion-by-lesion decision

The injection is considered for a lesion that is deep, firm, inflamed and tender, where calming it sooner is worth the small risk the injection carries. Typical examples are a large painful nodule on the face, a lesion that is distorting the skin, or one that has appeared before a wedding, an interview or a photograph. It is a decision made lesion by lesion, after looking at it and feeling it.

It is not the right tool in several situations:

A lump that is not typical of acne, such as one that persists without inflammation, grows steadily or bleeds, is examined as a lump in its own right before anything is injected.

“An injection calms the cyst in front of you. It does nothing about the next one; that is what treating the acne is for.”

Dr Sin YongOn cortisone injections for acne

Can a cortisone shot leave a dent? Atrophy and other side effects

It can. The commonest delayed side effect of intralesional corticosteroid, as DermNet describes it, is lipoatrophy: the fat beneath the injection site thins and leaves a small depression in the skin. A pale patch where pigment is reduced is the other common one, and it shows more in darker skin, which describes most skin in Singapore. Fine visible vessels at the site can also appear. These changes are more likely when the concentration is stronger, the volume larger, the injection too shallow, or the same spot is injected repeatedly. They often improve with time, but not always, and a dent that persists is a form of scar.

Early effects are the expected ones of any injection: a sting, brief bleeding, a small bruise, and tenderness. Infection is uncommon. Because the amount placed is small and stays where it is put, effects elsewhere in the body are not expected at the doses used for a single lesion.

That risk profile explains how the injection is used: dilute, placed in the centre of the lesion rather than the surrounding skin, and kept for lesions where the benefit is clear. It is also why the injection is part of a plan to stop new cysts forming. Each cyst prevented is a cyst that never needs injecting.

When to contact the clinic

Cortisone injection for acne in Singapore: what the visit involves

A cortisone injection for acne in Singapore is a short, doctor-performed procedure for one inflamed nodule or cyst, and the visit follows the same five steps every time. The section above explains what the injection does and does not do; this one sets out the visit itself, so that a request for a quick injection before an event is understood as one lesion treated inside a wider plan rather than as acne treatment.

young woman in her early twenties, bare face, calm, looking at camera, mild texture visible, no heavy makeup
Illustrative image — not a patient.
  1. The lesion is examined to confirm it is an inflamed acne nodule or cyst rather than a lookalike such as a boil, an infected cyst or a fungal lesion
  2. The local risks are explained: a small depression where the fat beneath the injection site thins, or a pale patch of skin, more likely in darker skin and with repeated injections into the same spot
  3. A dilute corticosteroid is injected directly into the single lesion by Dr Sin Yong, with the dose kept small for that lesion alone
  4. Aftercare is given: leave the lesion alone, no squeezing, sun protection over the site while it settles
  5. The lesion is reviewed, and the injection is placed within the wider acne plan, because a cyst that keeps recurring is nodulocystic acne and needs medical management rather than repeated injections

The last step is the one that decides whether the visit was the right one. Someone who needs an injection every few weeks for a new cyst is describing nodulocystic acne, the grade with the greatest risk of scarring, and the right response is to treat the acne rather than to keep injecting its lesions. Where a cyst has already left a mark or a dent, that is handled later, after the acne is controlled, on the acne scar treatment page.

Acne by life stage: teen, adult and pregnancy

The ladder on this page is the same at every age, but the starting rung and the medicines that are allowed change with life stage. Teenage acne is usually comedonal or papulopustular and begins with topical treatment and a time-limited oral course where the grade calls for it. Adult acne, particularly in women, more often clusters along the jawline and flares with the cycle, and the hormonal options are set out on the adult hormonal acne page. Acne in pregnancy or while breastfeeding rules out several of the usual medicines, including oral retinoids, and the choices that remain are covered in the pregnancy and breastfeeding guide. Which rung you start on is decided at assessment, not by age alone.

What else is needed besides the injection?

The injection settles the lesion in front of you. What is aimed at preventing the next one is acne treatment matched to severity. For cystic and nodular acne that is usually medical: guidelines support oral treatment, including antibiotic courses in defined roles, hormonal therapy in women where a hormonal pattern is confirmed, and oral isotretinoin for severe or scarring acne, each requiring a doctor's assessment and prescription. The acne treatment page sets out those options, and isotretinoin and aesthetic treatment timing explains how procedures are planned around that medicine.

In adult women, a cyclical pattern of deep lesions along the jaw and chin raises the question of a hormonal contribution, covered on the hormonal acne page. In teenagers, early control matters because scarring from this age can last into adult life. Where acne is severe, unusual or not responding, Dr Sin Yong, an aesthetic physician, refers to dermatology.

Scars are treated once acne is under control, because resurfacing over active disease treats a moving target. Scar depth then decides the method: FSX for superficial scars, the S3 Resurfacing Lift for deeper ones, subcision first for tethered scars and TCA CROSS for ice-pick scars. The acne to scar pathway page explains how a deep lesion becomes a scar, and why the time spent controlling acne is time saved later.

What decides the plan

The plan depends on how many deep lesions are forming, where they are, the skin type, any earlier injections at the same sites, pregnancy or other medical factors, and which medical treatment is already in place. The fee follows the plan agreed after examination; how we quote explains what the written quote contains.

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Note which lesions have been injected before, and when, so those sites are approached with care. How consultations work.

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Frequently Asked Questions

Yes, for a single inflamed nodule or cyst, after the lesion has been examined. A dilute corticosteroid is injected directly into that lesion to settle its inflammation. It acts on that one lesion only and carries local risks of a small dent or pale patch, so it is used sparingly and within a wider acne plan. Someone needing repeated injections is treated for the acne itself instead.
A pimple injection is the everyday name for a cortisone injection for acne: a small volume of dilute corticosteroid, usually triamcinolone, placed by a doctor into one deep, tender nodule or cyst. A pimple injection is not used for small surface spots or comedones, and it acts on the lesion injected, not on the acne that keeps producing new ones.
A cortisone injection for acne usually causes a brief sting from the fine needle and pressure inside an already tender cyst. In a 2023 clinical trial of 64 patients having triamcinolone injected into nodulocystic acne, mean pain scores were about 5.9 out of 10 without skin cooling and 3.7 with a cooling device. Tenderness afterwards mostly reflects the cyst itself.
Yes. In Singapore a cortisone shot is a prescription corticosteroid injection, so it is given by a doctor after the lesion has been examined. The doctor decides whether the lesion is a deep cyst that suits an injection, sets a dilute strength for facial skin, and checks for infection or earlier injections at the same site. At this practice on Orchard Road, suitability is confirmed at consultation.
A cortisone injection for acne uses a far more dilute strength than a keloid injection, because the skin over a facial cyst is thin and the risk of a dent rises with concentration. A 1983 randomised trial in nodulocystic acne found triamcinolone at 0.63 mg/mL as effective as 2.5 mg/mL, which supports using a low strength. The concentration and volume are set lesion by lesion.

The site is reviewed rather than injected again. Many dents and pale patches from intralesional corticosteroid improve with time as the fat and pigment recover, so the first step is usually to wait and compare photographs. A dent that persists once the acne is settled is assessed like any other atrophic acne scar, by type and depth, and the options on the acne scar pages apply.

Corticosteroid can reduce pigment production at the injection site, and a lighter patch shows more against Fitzpatrick IV to VI skin, which is common in Singapore. Dilute solutions, small volumes and placement in the centre of the lesion rather than the surrounding skin lower the risk. A pale patch that does appear is reviewed and given time, not treated over.

Sometimes, if the lesion is a deep, tender nodule or cyst rather than a surface pimple, and once it has been examined. It is not used for small spots or comedones, for a lesion that looks infected or full of pus, or at a site injected before. Ask early, because the lesion still needs time to settle.

The principle is the same, lesion by lesion, but acne on the trunk usually involves many lesions at once, so medical treatment matched to severity leads and an injection is kept for the occasional large, painful nodule. The chest, shoulders and upper back are also keloid-prone sites, so any raised scar there is assessed separately from the active acne, as the keloid steroid injection page explains.

Injecting every cyst treats each lesion while the acne continues, and repeat injections raise the risk of dents and pale patches. Frequent cysts mean the underlying acne needs medical treatment matched to its severity, such as oral therapy from a doctor. That is what is aimed at reducing new cysts and the scars they leave.

References

Intralesional steroid injection. DermNet (Lin CY), 2012. source

Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology (Reynolds RV et al.), 2024. source

Adult Female Acne: A Guide to Clinical Practice. Anais Brasileiros de Dermatologia, 2019. source

Intralesional corticosteroids in the treatment of nodulocystic acne. Archives of Dermatology, 1983. pubmed.ncbi.nlm.nih.gov

Cold anesthesia for pain reduction during intralesional steroid injection for nodulocystic acne. Journal of Cosmetic Dermatology, 2023. pubmed.ncbi.nlm.nih.gov

About this page: written and medically reviewed by Dr Sin Yong, MBBS (NUS), MRCS (Edinburgh) · Last reviewed 7 November 2026 · Illustrative images only, not patients · Editorial policy

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