Aftercare

Anti-wrinkle injection aftercare:
the first 24 hours and after

Medically reviewed by Dr Sin Yong · Last reviewed · 3 min read

The full guide to botulinum toxin in Singapore covers who it suits, the risks and how the dose is mapped.

A woman in her 30s, an illustrative image

After botulinum toxin injections, the first few hours matter most: do not rub or press the injected areas, avoid lying flat and strenuous exercise for about four hours, and leave facials and massages for a day or two. Small bumps and pinpoint bruises settle quickly. The effect appears over several days and is usually assessed at about two weeks.

What should you do and avoid after anti-wrinkle injections, phase by phase?

This table sets out anti-wrinkle injection aftercare by phase rather than by the clock: what is expected straight after botulinum toxin injections, in the early phase while the effect develops, and once it has settled, with what to do, what to avoid and the signs that mean you should message the clinic.

PhaseWhat is expectedWhat to doWhat to avoidMessage or call if
Straight afterSmall raised bumps at the injection points that flatten, pinpoint bruising, mild tendernessStay upright; keep the skin clean; hold a cool compress lightly on a bruiseRubbing, pressing or massaging the areas; lying flat; strenuous exercise; alcohol; tight headwearA bruise that spreads rather than fades; hives, wheezing or swelling of the lips
Early phaseBumps have gone; the effect is beginning and can look uneven while it developsNormal skincare, sunscreen and make-up applied gentlyFacials, facial massage, saunas, hot yoga; judging the result before it has settledA heavy brow or drooping eyelid; a smile that pulls to one side; a headache that is getting worse
SettlingThe effect is established and the review, if one is planned, falls in this phaseNote what was treated and when, so any adjustment is planned against the recordTop-ups elsewhere before the review; other treatments over the same muscles without askingDifficulty swallowing, speaking or breathing, generalised weakness or double vision: emergency care wherever you are

The marks, bruising and eyelid signs are described in more detail on anti-wrinkle injections downtime, travel timing is on flying after aesthetic treatment, and complication care sets out which signs go straight to an emergency department rather than to the clinic.

Mirror and soft window light
Illustrative image. Change appears over days, not hours.
Key facts
First 4 hours
No rubbing, pressing or lying flat; no strenuous exercise
First day or two
No facials, massages, saunas or tight headwear on the area
Make-up
Usually fine after a few hours, applied gently
When it works
Starts over several days; assessed at about 2 weeks
Flying
Same or next day
Urgent
Difficulty swallowing, speaking or breathing, or new weakness or double vision, hours to weeks later: emergency care
In this guide
  1. The first hours
  2. The days after
  3. Signs that need care
  4. Frequently Asked Questions

The first hours

Small raised bumps at the injection points are normal and flatten within an hour or so. Avoid rubbing, massaging or pressing on the areas, avoid lying flat, and avoid strenuous exercise for about four hours. Gentle facial expressions are fine. If a pinpoint bruise appears, a cool compress helps.

The days after

Leave facials, facial massage, saunas and tight hats or helmets that press on the area for a day or two. Normal skincare and make-up can be used gently. The effect begins over several days and settles by about two weeks, which is when any review is usually planned, in person or by photograph for visitors who have returned home.

Signs that need care

Mild headache or a feeling of heaviness can occur and usually passes. A drooping eyelid or uneven brow, if it happens, is assessed rather than waited out without advice. Difficulty swallowing, speaking or breathing, generalised weakness, double or blurred vision or drooping eyelids are rare, can appear hours to weeks after injection, and need emergency care.

Questions after treatment come back through WhatsApp at +65 8023 7170 during clinic hours (Monday to Friday 10am to 8pm, Saturday 11am to 3pm, Singapore time). Anything that is getting worse rather than better, a blister or open area, or fever needs to be seen the same day, wherever you are.

Frequently Asked Questions

Avoid lying flat for about four hours.

Avoid strenuous exercise for about four hours; light activity is fine.

It starts over several days and is usually assessed at about two weeks.

Yes, usually the same or next day; there is no good evidence that cabin pressure moves the toxin.

Speak With Dr Sin Yong

Consultations by appointment at Orchard Road, Singapore.

  1. 1WhatsApp a short note on your concern and your travel dates
  2. 2Consultation and assessment with Dr Sin Yong
  3. 3Options explained, including no treatment

Replies within clinic hours: Mon–Fri 10am–8pm, Sat 11am–3pm (Singapore time, GMT+8) · How consultations work · Call +65 8023 7170 · Map

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References

  1. Efficacy and Safety of Botulinum Toxin Type A for Treatment of Glabellar Lines: A Network Meta-Analysis of Randomized Controlled Trials. Dermatologic Surgery, 2022. pubmed.ncbi.nlm.nih.gov
  2. Consensus Recommendations for Combined Aesthetic Interventions Using Botulinum Toxin, Fillers, and Energy-Based Devices. Dermatologic Surgery, 2016. pubmed.ncbi.nlm.nih.gov
  3. The Role of Botulinum Toxin for Masseter Muscle Hypertrophy: A Comprehensive Review. Toxins, 2025. pubmed.ncbi.nlm.nih.gov
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