Medically reviewed by Dr Sin Yong · Last reviewed · 3 min read
See also: PDO vs PCL vs PLLA threads.
See also: which thread: PDO, PCL or PLLA.
The same polydioxanone material is used along the nasal bridge in a nose threadlift.
Published 13 October 2026 · Reviewed by Dr Sin Yong

PDO thread is an absorbable thread made of polydioxanone, the polymer used in absorbable surgical sutures, placed in the subcutaneous plane to reposition descended tissue or to leave a track of new collagen. It is firm with limited stretch and, of the three thread polymers (PDO, PLLA and PCL), it hydrolyses earliest, so its mechanical hold tapers first while the collagen track remains. In Dr Sin Yong's Bliss Lift it is the material used for most jowl and midface vectors.
PDO is the workhorse thread polymer on this site, and the pages below are where it is chosen, compared with other routes, or dealt with when a thread has gone wrong.
A thread repositions tissue that has dropped; it cannot replace volume that has gone or remove skin that is in excess.— Dr Sin Yong
Regulatory status. Polydioxanone is the polymer of absorbable surgical sutures. Threads made from it are medical devices, and in Singapore medical devices are regulated by the Health Sciences Authority; see how aesthetic medicine is regulated in Singapore.
Threads are often discussed as one thing, but the material and the procedure change what they can do.
On a treatment menu, "PDO" may describe smooth threads placed for skin quality or barbed threads placed for a lift. They are different procedures with different aims, and it is worth asking which is being proposed.
Material is chosen per vector, not per face, and only after the face has been judged suitable for threads at all.
Where a different mechanism suits better, Dr Sin Yong says so; the thread lift limitations guide sets out when he declines.
A thread lift is a mechanical lift: a barbed PDO cog thread engages the fat and fibrous septae it passes through, and tension toward a fixed anchor at the temple or in front of the ear carries that tissue with it. It does not heat tissue, add volume or remove skin, which is why it suits early to moderate descent of the jowl, midface and brow rather than heavy laxity or established skin excess. Threads resorb on their own timeline and cannot be dissolved on demand, unlike hyaluronic acid filler. Material is chosen per vector, not per face. Full page: the Bliss Lift; the term on thread lift; threads in the nose on nose thread lift.
Related
Guide: thread lift Singapore — PDO, PCL and PLLA threads, what they can and cannot do.
Not on demand. Polydioxanone resorbs by hydrolysis on its own timeline; there is no dissolving enzyme as there is for hyaluronic acid filler. A thread that is visible or misplaced is managed at assessment, which is one reason planning and plane matter.
Both, chosen per vector. PDO is firm and resorbs earliest, so it carries most jowl and midface vectors in the Bliss Lift; PCL is more flexible and resorbs slowest, so it is chosen where tissue is heavier or support needs to last longer.
Update on Absorbable Facial Thread Lifts. Dermatologic Surgery (PubMed), 2025. pubmed.ncbi.nlm.nih.gov
Outcomes of polydioxanone knotless thread lifting for facial rejuvenation. Dermatologic Surgery (PubMed), 2015. pubmed.ncbi.nlm.nih.gov
Lifting the Lower Face With an Absorbable Polydioxanone (PDO) Thread. Journal of Drugs in Dermatology (PubMed), 2017. pubmed.ncbi.nlm.nih.gov
Consultations by appointment at Orchard Road, Singapore.
Replies within clinic hours: Mon–Fri 10am–8pm, Sat 11am–3pm · How consultations work · Prefer not to use WhatsApp? · Treatment finder
WhatsApp +65 8023 7170 →