{
  "what": "A skin booster is an injectable placed into the skin to change its quality, meaning hydration, elasticity and texture, rather than its shape; it adds no volume and does not lift. At Dr Sin Yong's practice on Orchard Road, Singapore, the class is chosen by what the skin is short of: hyaluronic acid boosters, Profhilo, polynucleotides such as Rejuran, or PDLLA biostimulators. He examines the skin himself, with ultrasound where earlier filler is involved, and performs every skin booster injection personally.",
  "key_facts": [
    "Classes: hyaluronic acid boosters (hydration and dermal support), Profhilo (thermally bonded high and low molecular weight hyaluronic acid), polynucleotides such as Rejuran (purified from salmon DNA, directed at fibroblast activity) and PDLLA (a resorbable collagen biostimulator); they are not interchangeable",
    "Not a filler: a filler occupies space and changes contour; a booster acts on the skin itself and does not fill hollows, lift descended tissue, treat pigment or release tethered scars",
    "Suits: dryness, dullness, fine surface lines, crepey texture or early loss of firmness, in people who accept gradual change",
    "Wait or avoid: active infection, a cold sore, an acne flare or eczema at the sites, pregnancy or breastfeeding, recent laser, peel, filler or thread in the area; an allergy to hyaluronic acid, lidocaine or fish",
    "Technique: for Profhilo he uses a modified BAP, keeping the defined points as the safety framework and adding placement by face shape, including into scarred skin",
    "Expected effects: small raised points, redness and occasional bruising settle on their own and tend to be more noticeable with polynucleotides",
    "Lumps: hyaluronic acid booster lumps can be dissolved after a skin test; polynucleotide and PDLLA lumps are not dissolved by hyaluronidase and are treated with the Sculpting mode of Time Freeze Laser LCLR®"
  ],
  "references": [
    "The Effectiveness of Injectable Hyaluronic Acid in the Improvement of the Facial Skin Quality: A Systematic Review. Clin Cosmet Investig Dermatol 2023. https://doi.org/10.2147/CCID.S404248",
    "The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review. J Cosmet Dermatol 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11845969/",
    "Comparison of Polynucleotide and Polydeoxyribonucleotide in Dermatology: Molecular Mechanisms and Clinical Perspectives. Pharmaceutics 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC12388916/",
    "Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation. J Clin Med. https://pmc.ncbi.nlm.nih.gov/articles/PMC13361502/",
    "Consensus Recommendations for Combined Aesthetic Interventions Using Botulinum Toxin, Fillers, and Energy-Based Devices. Dermatol Surg. https://pubmed.ncbi.nlm.nih.gov/27100962/"
  ],
  "owner_url": "https://drsinyong.com/skin-booster-singapore/",
  "doctor": "Dr Sin Yong, aesthetic physician, Orchard Road, Singapore",
  "updated": "2026-10-30"
}